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WESTPORT, Conn., Nov. 26, 2024 (GLOBE NEWSWIRE) -- Portage Biotech Inc. (“Portage” or the “Company”) (NASDAQ: PRTG), a clinical-stage immuno-oncology company with a portfolio of novel multi-targeted therapies for use as monotherapy and in combination, today reported its financial results for the fiscal quarter ended September 30, 2024. “We are continuing to explore multiple strategic alternatives to further unlock shareholder value. These may include finding a partner for one or more of our assets, a sale of our company, a merger, restructurings (both in and out of court), a company wind down, further financing efforts, or other strategic actions,” said Dr. Ian Walters, Chief Executive Officer and Chairman of Portage. “The ADPORT-601 trial is paused for further patient accrual pending additional financial resources, and we are analyzing the data. We also continue our collaborations with numerous experts to further understand the biology and utility of our product candidates,” continued Dr. Walters. Financial Results for the Quarter Ended September 30, 2024 The Company incurred a net loss of approximately $1.4 million during the three months ended September 30, 2024 (the “Fiscal 2025 Quarter”), compared to a net loss of approximately $5.2 million during the three months ended September 30, 2023 (the “Fiscal 2024 Quarter”), representing a $3.8 million decrease quarter-over-quarter. Operating expenses, including research and development (“R&D”) costs and general and administrative (“G&A”) expenses, were $1.6 million in the Fiscal 2025 Quarter, down from $5.9 million in the Fiscal 2024 Quarter, a decrease of $4.3 million, as detailed below. R&D costs decreased by approximately $3.5 million, or approximately 83%, from approximately $4.2 million in the Fiscal 2024 Quarter to approximately $0.7 million in the Fiscal 2025 Quarter. The decrease was primarily attributable to the winding down of clinical trial costs (principally CRO-related), which decreased by approximately $1.6 million, from $2.0 million in the Fiscal 2024 Quarter to $0.4 million in the Fiscal 2025 Quarter, as activities ramped down throughout the period since we made the decision to pause enrollment in our sponsored clinical trials in the third and fourth quarters of Fiscal 2024. Manufacturing-related costs decreased by $0.9 million, from $1.0 million in the Fiscal 2024 Quarter to $0.029 million in the Fiscal 2025 Quarter. These decreases reflect the winding down of clinical activity and manufacturing-related costs resulting from our decision to discontinue our sponsored clinical trial for the iNKT program and pause further patient accrual to our sponsored adenosine program. R&D non-cash share-based compensation expense decreased from $0.4 million in the Fiscal 2024 Quarter to nil in the Fiscal 2025 Quarter. Payroll-related expenses decreased by $0.1 million, from $0.37 million in the Fiscal 2024 Quarter to $0.24 million in the Fiscal 2025 Quarter, due to the resignation of two employees in January 2024. Additionally, consulting fees decreased by approximately $0.2 million from $0.25 million in the Fiscal 2024 Quarter to $0.03 million in the Fiscal 2025 Quarter, to reflect the decrease in activity period-over-period. Finally, licensing fees decreased by approximately $0.1 million due to licensing fees paid to the licensor of certain intellectual property utilized in the iNKT clinical trial in Fiscal 2024 Quarter compared to nil in Fiscal 2025 Quarter as the iNKT clinical trial was discontinued in the latter half of Fiscal 2024. G&A expenses decreased by approximately $0.8 million, or approximately 48%, from approximately $1.7 million in the Fiscal 2024 Quarter to approximately $0.9 million in the Fiscal 2025 Quarter. Professional fees decreased by $0.4 million, from $0.8 million in the Fiscal 2024 Quarter to $0.4 million in the Fiscal 2025 Quarter. Payroll-related expenses decreased by $0.1 million from $0.2 million in the Fiscal 2024 Quarter to $0.1 million in the Fiscal 2025 Quarter. The decrease in professional fees and payroll-related expenses is due to the accrual of the monthly fees and payments for the entire second quarter in the first quarter for a consultant and employee in connection with certain Retention Agreements entered into on July 22, 2024. Additionally, G&A non-cash share-based compensation expense decreased by $0.2 million due to the continued vesting of stock options, partially offset by recording all share-based compensation expense as G&A expenses as the result of the discontinuation of the iNKT trial and the pause of further patient accrual in the adenosine program. Finally, directors’ fees decreased by $0.1 million in the Fiscal 2025 Quarter, compared to the Fiscal 2024 Quarter, as all directors, except for two directors who resigned in April 2024, waived their fees in the Fiscal 2025 Quarter. The primary reasons for the quarter-over-quarter differences in the Company’s pre-tax items of income and expense were the $0.9 million net gain from the settlement and release of obligations and liabilities under the Master Services Agreement between iOx and Parexel partially offset to some extent by the $0.7 million non-cash loss from the change in the fair value of certain warrants accounted for as liabilities, issued in connection with a private placement offering in October 2023, both in the Fiscal 2025 Quarter, and a non-cash loss from the increase in the fair value of the deferred purchase price payable to the former Tarus shareholders and the deferred obligation for the iOx milestone, totaling $0.1 million, in the Fiscal 2024 Quarter. As of September 30, 2024, the Company had cash and cash equivalents of approximately $1.8 million and total current liabilities of approximately $0.9 million. About Portage Biotech Inc. Portage is a clinical-stage immuno-oncology company with a portfolio of multi-targeted therapies to extend survival and significantly improve the lives of patients with cancer. The Company has made the decision to discontinue its sponsored trial for its the invariant natural killer T-cell (iNKT) program and pause further patient accrual to its sponsored adenosine trial program (ADPORT-601 trial) for its potentially best-in-class adenosine antagonists PORT-6 (adenosine 2A inhibitor) and PORT-7 (adenosine 2B inhibitor). The Company is exploring strategic alternatives, which may include finding a partner for one or more of its assets, a sale of the company, a merger, restructurings, both in and out of court, a company wind down, further financing efforts or other strategic actions. For more information, please visit www.portagebiotech.com or find us on LinkedIn at Portage Biotech Inc. Forward-Looking Statements All statements in this news release, other than statements of historical facts, including without limitation, statements regarding about the Company’s information that are forward-looking in nature and, business strategy, plans and objectives of management for future operations and those statements preceded by, followed by or that otherwise include the words "believe," "expects," "anticipates," "intends," "estimates," “will,” “may,” “plan,” “potential,” “continue,” or similar expressions or variations on such expressions are forward-looking statements. For example, statements regarding the Company's plans to continue exploring strategic alternatives, which may include finding a partner for one or more of its assets, a sale of the company, a merger, restructurings (both in and out of court), a company wind down, further financing efforts, or other strategic actions, the Company’s expectation to replace one patient in the ADPORT-601 trial, and the Company’s plans to continue its collaborations with numerous experts to further understand the biology and utility of its product candidates are forward-looking statements. As a result, forward-looking statements are subject to certain risks and uncertainties, including, but are not limited to: the Company's plans and ability to develop and commercialize product candidates and the timing of these development programs; the Company's clinical development of its product candidates, including the results of current and future clinical trials; the benefits and risks of the Company's product candidates as compared to others; the Company's maintenance and establishment of intellectual property rights in its product candidates; the Company's ability to obtain financing in the future to cover its operational costs and progress its plans for clinical development, its estimates regarding its capital requirements, and its ability to continue as a going concern; the Company’s estimates of future revenues and profitability; the Company's estimates of the size of the potential markets for its product candidates; its selection and licensing of product candidates; and other factors set forth in “Item 3 - Key Information-Risk Factors” in the Company’s Annual Report on Form 20-F for the year ended March 31, 2024 2024 and “Business Environment – Risk Factors” in the Company’s Management’s Discussion and Analysis for the Three and Six Months ended September 30, 2024 filed as Exhibit 99.2 to the Company’s Form 6-K. Although the Company believes that the expectations reflected in these forward-looking statements are reasonable, undue reliance should not be placed on them as actual results may differ materially from these forward-looking statements. The forward- looking statements contained in this news release are made as of the date hereof, and the Company undertakes no obligation to update publicly or revise any forward-looking statements or information, except as required by law. FOR MORE INFORMATION, PLEASE CONTACT: Investor Relations: ir@portagebiotech.com Media Relations: media@portagebiotech.com ---tables to follow--- PORTAGE BIOTECH INC. Condensed Consolidated Interim Statements of Operations and Other Comprehensive Income (Loss) (U.S. Dollars in thousands, except per share amounts) (Unaudited) PORTAGE BIOTECH INC. Condensed Consolidated Interim Statements of Financial Position (U.S. Dollars in thousands) (Unaudited)
Simone Inzaghi insists Inter deserve a great deal of credit for , which puts them temporarily top of the Champions League table. ‘I know my team is mature.’ The Nerazzurri were perhaps expecting a slightly more comfortable evening at San Siro, but failed to take their chances and saw a late Henrikh Mkhitaryan goal controversially disallowed over a soft Marcus Thuram foul. Ultimately, Castello Lukeba accidentally turning a Federico Dimarco free kick into his own net proved sufficient to beat RB Leipzig and put them on 13 points, temporarily top of the Champions League table. They are also the only side remaining yet to concede a single goal, as Atalanta broke their perfect record with a 6-1 victory away to Young Boys. “Naturally, we are satisfied, because we knew how important this evening’s game was. It’s true Leipzig have zero points in the table, but until last Saturday they were second in the Bundesliga with the best defence in the league. They have a lot of quality, are well-drilled,” “We had to maintain a balance and it was not easy against a very aggressive side that presses high. The one issue was not scoring the second goal, but apart from a single Yann Sommer save, we didn’t really suffer very much.” Inter had a lot of possession, but ultimately struggled to create many clear scoring opportunities this evening against RB Leipzig. “I agree that if we look at the amount of possession we had, the Dumfries chance straight after the restart probably could’ve directed the match on a different level, while I have doubts about the disallowed Mkhitaryan goal,” continued Inzaghi. “Overall though, Openda, Sesko, Nusa, they are all very talented players we were up against and it is no surprise they were in the 2020 semi-final and have been in the Champions League for six years in a row. “We needed the Inter performance that I wanted and saw, constantly focused and ready to cover every space.” The Nerazzurri also seemed to lose intensity in the final 20 minutes, so was there a reason for that? “Without the second goal, we got a bit deeper in the final stages, especially as we knew Leipzig by introducing Sesko could create a goal out of nothing,” concluded Inzaghi. “With the fixture list the way it is, we need to rotate the squad and we also lost Pavard today, so we hope to have him back soon.” Benjamin Pavard limped off just before half-time with initial reports pointing to a flexor issue in his left thigh. With 13 points from six rounds, Inter are now temporarily top of the table awaiting Liverpool on Wednesday night. “We’re pleased to be there, but also know there is still a big step before we can guarantee a place in the top eight. We’ve got Bayer Leverkusen, then Sparta Prague and Monaco will be tough too,” added Inzaghi. “We won four in a row without conceding and that too is pleasing, especially considering the quality of the opponents that we faced. I was honestly concerned about this match, but I also knew that my team was mature enough to know that Leipzig’s current position does not reflect the quality of the side.” Inter reached the Champions League Final in 2023 and it is their target to get back there at the end of the current campaign. “That is the objective for all the big clubs, especially for me as I am at Inter. We know it is not easy playing every two and a half days, it really takes a lot out of you, so I am fortunate to have these lads. They are all willing to do the extra work,” noted Inzaghi.Nagpur, Dec 25 (PTI) Maharashtra minister Chandrashekhar Bawankule on Wednesday said the pending elections to local bodies in the state will be held in March-April 2025 if the Supreme Court gives its decision on the OBC reservation in the first week of January. Addressing a press conference here, he said a hearing on the quota for the Other Backward Classes (OBC) is listed in the apex court in the first week of January. "The State Election Commission will conduct the polls and the state government will provide all the support," the Revenue Minister said. The five-year term of most of the municipal corporations, including the Brihanmumbai Municipal Corporation (BMC), and other local bodies in the state expired in 2022. In December 2021, the Supreme Court had ruled that reservation for OBCs in local bodies will not be allowed unless the government fulfils the triple test laid down in the apex court's 2010 order. It had ruled that until the triple test criteria is fulfilled, the OBC seats will be re-notified as general category seats. The triple test required the state government to set up a dedicated commission to gather data on the backwardness of OBCs in every local body, to specify the proportion of reservation in each local body in light of commission’s recommendations, and ensure that such reservation does not exceed 50 per cent of the total seats reserved for SC/ST/OBC together. Bawankule further said there were complaints that several properties owned by private charitable trusts and educational institutions were forcibly taken over by the Waqf Board in Maharashtra. "Once the Waqf (Amendment) Bill is cleared by Parliament, it will be implemented in Maharashtra. If there are any wrongdoings, they will be rectified," he said. The Maharashtra BJP chief said that under the Survey of Villages Abadi and Mapping with Improvised Technology in Village Areas (SVAMITVA), the process to conduct a drone survey of villages began in 2021 to provide e-property cards to farmers for ownership of their land in rural areas. The e-property cards in 15,327 of the 30,515 villages are ready and will be distributed soon, he said. (This story has not been edited by THE WEEK and is auto-generated from PTI)
BOZEMAN, Mont. (AP) — Tommy Mellott threw for 300 yards and four touchdowns and top-seeded Montana State tied a school record with its 13th straight win, dominating Tennessee-Martin 49-17 on Saturday in the second round of the FCS playoffs. Scottre Humphrey ran for 102 yards and a touchdown, one of three rushing touchdowns for the Bobcats (13-0), who are home next weekend against the winner of Saturday's late game between Lehigh and eighth-seeded Idaho. MSU, which has scored at least 30 points in every game this season, won 13 games in 1975-76. Mellott threw for 178 yards and three touchdowns in the first half and the Bobcats rolled to a 28-10 lead. Mellott had touchdown passes of 24 yards to Hunter Provience and 12 yards to Taco Dowler in the first quarter and 39 yards to Ty McCullouch in the second. McCullouch also had a 6-yard touchdown run. The pass to McCullouch ended a six-play, 73-yard drive that took just 53 seconds, and came immediately after Trevonte Rucker took a pass from Kinkead Dent 78 yards to the end zone that made it 21-10. The Bobcats only allowed only 10 total points in the first half of home games in the regular season. Humphrey had a 36-yard TD run and Mellott hit Dowler for a 29-yard score in the third quarter Adam Jones contributed a 30-yard scoring run in the fourth. Mellott finished 22-of-25 passing and the Bobcats had 501 total yards. Dent threw for 167 yards and two touchdowns, both to Rucker, who had six receptions for 107 yards. The Skyhawks (9-6) finished with 264 yards. AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football . Sign up for the AP’s college football newsletter: https://apnews.com/cfbtop25Californians assessing damage from earthquake after tsunami warnings lifted Aftershocks are being felt in California after a major earthquake struck off the coast near Eureka, triggering tsunami warnings that were later lifted. CBS News Bay Area has continuing coverage as locals take stock of damage from the earthquake.Elizabeth Olsen Details Financial Problems of Todd Solondz’s Love Child
Heartbreak as teen backpackers' bodies return homeNone
Jonah Goldberg: What if most Americans aren't bitterly divided?
Jonah Goldberg Among elites across the ideological spectrum, there's one point of unifying agreement: Americans are bitterly divided. What if that's wrong? What if elites are the ones who are bitterly divided while most Americans are fairly unified? History rarely lines up perfectly with the calendar (the "sixties" didn't really start until the decade was almost over). But politically, the 21st century neatly began in 2000, when the election ended in a tie and the color coding of electoral maps became enshrined as a kind of permanent tribal color war of "red vs. blue." Elite understanding of politics has been stuck in this framework ever since. Politicians and voters have leaned into this alleged political reality, making it seem all the more real in the process. I loathe the phrase "perception is reality," but in politics it has the reifying power of self-fulfilling prophecy. Like rival noble families in medieval Europe, elites have been vying for power and dominance on the arrogant assumption that their subjects share their concern for who rules rather than what the rulers can deliver. In 2018, the group More in Common published a massive report on the "hidden tribes" of American politics. The wealthiest and whitest groups were "devoted conservatives" (6%) and "progressive activists" (8%). These tribes dominate the media, the parties and higher education, and they dictate the competing narratives of red vs. blue, particularly on cable news and social media. Meanwhile, the overwhelming majority of Americans resided in, or were adjacent to, the "exhausted majority." These people, however, "have no narrative," as David Brooks wrote at the time. "They have no coherent philosophic worldview to organize their thinking and compel action." Lacking a narrative might seem like a very postmodern problem, but in a postmodern elite culture, postmodern problems are real problems. Listen now and subscribe: Apple Podcasts | Spotify | Stitcher | RSS Feed | SoundStack | All Of Our Podcasts It's worth noting that red vs. blue America didn't emerge ex nihilo. The 1990s were a time when the economy and government seemed to be working, at home and abroad. As a result, elites leaned into the narcissism of small differences to gain political and cultural advantage. They remain obsessed with competing, often apocalyptic, narratives. That leaves out most Americans. The gladiatorial combatants of cable news, editorial pages and academia, and their superfan spectators, can afford these fights. Members of the exhausted majority are more interested in mere competence. I think that's the hidden unity elites are missing. This is why we keep throwing incumbent parties out of power: They get elected promising competence but get derailed -- or seduced -- by fan service to, or trolling of, the elites who dominate the national conversation. There's a difference between competence and expertise. One of the most profound political changes in recent years has been the separation of notions of credentialed expertise from real-world competence. This isn't a new theme in American life, but the pandemic and the lurch toward identity politics amplified distrust of experts in unprecedented ways. This is a particular problem for the left because it is far more invested in credentialism than the right. Indeed, some progressives are suddenly realizing they invested too much in the authority of experts and too little in the ability of experts to provide what people want from government, such as affordable housing, decent education and low crime. The New York Times' Ezra Klein says he's tired of defending the authority of government institutions. Rather, "I want them to work." One of the reasons progressives find Trump so offensive is his absolute inability to speak the language of expertise -- which is full of coded elite shibboleths. But Trump veritably shouts the language of competence. I don't mean he is actually competent at governing. But he is effectively blunt about calling leaders, experts and elites -- of both parties -- stupid, ineffective, weak and incompetent. He lost in 2020 because voters didn't believe he was actually good at governing. He won in 2024 because the exhausted majority concluded the Biden administration was bad at it. Nostalgia for the low-inflation pre-pandemic economy was enough to convince voters that Trumpian drama is the tolerable price to pay for a good economy. About 3 out of 4 Americans who experienced "severe hardship" because of inflation voted for Trump. The genius of Trump's most effective ad -- "Kamala is for they/them, President Trump is for you" -- was that it was simultaneously culture-war red meat and an argument that Harris was more concerned about boutique elite concerns than everyday ones. If Trump can actually deliver competent government, he could make the Republican Party the majority party for a generation. For myriad reasons, that's an if so big it's visible from space. But the opportunity is there -- and has been there all along.Can Ethereum Break $3,500 Before End Of 2024, Discover the Top 7 Next Crypto to Explode Even Faster
KINGSTON, Jamaica – The United Independents’ Congress of Jamaica (UIC Jamaica) has called for a speedier ruling in the case of its leader Joseph Patterson who is challenging the constitutionality of his 2021 arrest and charge over a public protest during the heights of the COVID-19 pandemic. “The optics is one of the prime minister using the courts to silence his political opponent and slow the rise of Jamaica’s official third registered political party,” claimed the UIC in a press release Thursday signed by its caretaker for Westmoreland Eastern Winston Wright. Patterson was among several persons arrested during a public march organised by the UIC in downtown Kingston. They were demonstrating against mandatory COVID-19 vaccines – despite no such mandates being given by the Jamaican government – and demanding the resignation of all 63 members of parliament. The UIC head subsequently brought a constitutional challenge before the Supreme Court alleging that his arrest was unlawful and a violation of his rights. “The Andrew Holness-led administration overstepped its bounds when it used the police force to assault, arrest and jail him and others during resistance to their improper response to the COVID-19 pandemic,” the UIC release stated. “These unconstitutional actions occurred in Kinston at the UIC’s Freedom March on September 22, 2021, which Mr Patterson led as President of Jamaica’s third officially registered political party,” the UIC continued. “The Constitutional Court, after delaying Mr Patterson’s hearing for nearly three years, heard the case eventually and gave its assurance of a ruling by July 31, 2024, but has to date still not delivered a verdict. Clearly, this is justice delayed and justice delayed is justice denied!” The party claims the case is expected to be precedent-setting as it challenges the colonial era Public Order Act and seeks to clarify the powers of the prime minister’s national emergencies. Patterson is reportedly still required to regularly appear before the lower courts in Half Way Tree and Mandeville as he is still on bail which affects his livelihood as an internationally Chartered Professional Accountant. The release says he was initially denied station bail by the police “which was apparently acting on cues from what appears to be a very vindictive and tyrannical Government which misused the police as part of its effort to impose the will of its foreign masters on the people of Jamaica.” Immediately following the incident, the Jamaica Constabulary Force (JCF) had said via Facebook, “The police have arrested the main organiser of the protest, Joseph L Patterson, following his non-compliance with the provisions under the Public Order Act. Jamaican laws require that individuals organizing public marches must get a permit from the police. No permit was sought and none was granted.” The statement was accompanied by a video of Patterson being firmly pulled away from the protest into a police vehicle. Citing what it said has been the relatively speedy progress of a case brought before the court by the prime minister, the UIC has alleged double standard. “Jamaicans have all seen where Mr Holness was able to bring his case before the Supreme Court in less than 90 days while Mr Patterson had to wait some 1, 000 days, nearly three years for his case to be heard. The Chief Justice (Bryan Sykes) needs to explain this glaring bias,” the UIC said.ALBANY (NY) (5-3) Adewale 0-2 0-0 0, Klaczek 0-5 4-4 4, Briggs 4-9 6-6 17, Marshall 3-7 9-10 17, Strand 1-4 2-2 5, Neely 6-14 0-0 12, Matulu 1-1 0-0 2, Lindsey 4-5 0-0 8, Taylor 1-4 0-0 3, Adnan 0-2 0-0 0, Reddish 0-1 0-0 0, Topuz 0-2 0-0 0, Giralt 0-0 0-2 0. Totals 20-56 21-24 68. GEORGETOWN (6-1) Fielder 3-6 3-3 10, Sorber 6-9 1-1 14, Epps 4-7 0-0 8, Mack 6-8 1-1 16, Peavy 9-14 3-3 24, Burks 5-6 0-0 11, Mulready 1-3 0-0 2, Ca.Williams 4-6 1-1 9, Cu.Williams 2-3 0-0 4, McKenna 1-1 0-0 2, Asadallah 0-1 0-0 0, Montgomery 0-1 0-0 0, Van Raaphorst 0-0 0-0 0. Totals 41-65 9-9 100. Halftime_Georgetown 49-35. 3-Point Goals_Albany (NY) 7-22 (Briggs 3-5, Marshall 2-3, Strand 1-3, Taylor 1-3, Adnan 0-1, Reddish 0-1, Topuz 0-1, Klaczek 0-2, Neely 0-3), Georgetown 9-22 (Mack 3-4, Peavy 3-6, Burks 1-2, Fielder 1-2, Sorber 1-2, Montgomery 0-1, Cu.Williams 0-1, Epps 0-2, Mulready 0-2). Rebounds_Albany (NY) 21 (Neely 5), Georgetown 33 (Sorber 13). Assists_Albany (NY) 6 (Marshall, Neely 2), Georgetown 26 (Peavy 8). Total Fouls_Albany (NY) 14, Georgetown 17. A_4,227 (20,356).
Strap in, science enthusiasts! The future has arrived. 2025 is gearing up to be an epic year of scientific showdowns and breakthroughs. Picture a world where nuclear reactors power up cities as fast as quantum computers solve complex problems, and brain-computer interfaces unlock human potential like never before. This isn’t the plot of a sci-fi blockbuster, but this could be the world in 2025. From bold space explorations to pioneering particle physics experiments, the coming year is set to be a spectacular showcase of innovation. Prepare to be amazed as we take you through seven scientific and technological revolutions about to unfold in 2025. Nuclear energy boom As the global demand for clean and scalable energy solutions ignited the spark for nuclear energy with tech giants betting big on it. In 2024, the world embraced the nuclear renaissance. Now, 2025 will be the crucial ‘prove-it’ year for nuclear energy’s resurgence. Approximately 65 nuclear reactors are under construction in 16 countries, with plans to complete 12 by 2025. Notably, India and China each complete three, while Bangladesh and Russia add two each, and South Korea and Turkey add one each. Around 90 reactors with a combined capacity of roughly 90 GWe are planned, with over 300 more proposed, predominantly in Asian nations where economic growth and electricity demand are rapidly increasing. Despite new reactors coming online, the number of operational reactors has remained relatively stable due to the retirement of older units. Over the past two decades, 107 reactors were retired while 100 new reactors began operations. Presently, about 440 nuclear reactors are in operation across 32 countries worldwide, including Taiwan, with a total capacity of about 390 GWe. In 2023, these reactors contributed approximately 2,602 TWh, accounting for about 9% of the global electricity supply. Recognizing the potential of advanced nuclear technologies to meet sustainability objectives, tech giants such as Google are making substantial investments in this sector. Notably, Google has also collaborated with Kairos Power to integrate nuclear energy into its grid, complementing its reliance on renewable sources like wind and solar. The future of nuclear power looks promising, with projections indicating a nearly 3 percent annual growth in global nuclear power generation through 2026, setting new records by 2025. This optimistic outlook was bolstered by a joint declaration signed at the COP28 climate conference in December 2023, where over 20 countries committed to tripling nuclear capacity by 2050, translating to an additional 740 GW. Innovations in nuclear technology continue to evolve, with developments such as Small Modular Reactors (SMRs) offering versatile and efficient solutions. This trajectory is not only taking us to a greener tomorrow but also contributing to local economic growth and job creation. Closing in on the quantum age Quantum computing, a concept that has fascinated physicists for over four decades, is quickly realizing practical applications. This technology, rooted in the principles of quantum physics, offers processing capabilities far beyond those of traditional computers. It is set to amplify our scientific endeavors by enabling the modeling of complex phenomena that classical computers can’t efficiently process. Recent advancements have edged “quantum utility” closer than ever. For example, Google’s latest quantum processor , Willow, demonstrated its potential by solving a computational problem in just five minutes, that the most powerful supercomputers could not tackle within the age of the universe. This achievement highlights the unique ability of quantum computers to manage tasks with an extensive array of variable inputs, making them particularly suitable for simulating complex systems, from molecular interactions in drug development to tricky economic forecasts. The commercial quantum computing landscape has seen significant contributions from pioneers like Canadian-based D-Wave Quantum Inc., which in 2011 became the first company to sell quantum computers. Major tech entities such as IBM, Google, and Amazon Web Services and startups like Universal Quantum and PsiQuantum Corp. are actively developing this technology. Notably, companies including Microsoft and Intel are progressing towards building scalable, practical quantum supercomputers, with Intel shipping a silicon quantum chip with notably smaller qubits than conventional designs. Despite their prowess, quantum computers are not intended to replace conventional computers for everyday tasks that involve sequential processing of simpler, isolated data sets. Instead, they are being developed to handle high-complexity problem-solving. Looking ahead to 2025, the quantum computing field is expected to achieve critical milestones such as increased qubit count and coherence times, advancements in quantum algorithms, integration with classical supercomputers, improvements in quantum error correction, and broader adoption of quantum-safe cryptography. Connecting minds and machines with BCI in 2025 Entering 2025, the brain-computer interface (BCI) frontier is witnessing significant developments, particularly in China . The country’s Ministry of Industry and Information Technology has outlined ambitious plans to pioneer BCI devices that span a range of applications from medical rehabilitation to virtual reality enhancements. A standout innovation is NEO, a wireless, minimally invasive BCI system equipped with eight electrodes. This device, positioned over the brain’s sensorimotor cortex, is specifically engineered to restore hand mobility in individuals with paralysis. NEO’s clinical trials, initiated in 2023, have already shown promising outcomes. After nine months of home use, a participant with a spinal cord injury regained the ability to perform daily tasks such as eating and drinking independently. Plans are in place to move the implant to larger-scale trials by 2025. In the realm of fully implantable BCIs, Paradromics emerges as a notable player. It distinguishes itself by recording from single neurons and utilizing durable materials that enhance the longevity and safety of the implants. The company is gearing up for its clinical trials slated for 2025. Meanwhile, New York-based Synchron is making strides in the United States by integrating generative AI technology into its endovascular BCI systems. This development aims to enhance communication capabilities for individuals with motor impairments, allowing for more interactive and intuitive use of BCI platforms. Technological advancements are also expected in non-invasive BCIs, such as those utilizing electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS). Improvements are also anticipated in areas like materials science and device miniaturization, leading to less invasive devices and ones which are more compatible with human tissue. The scope of BCI applications is expanding, with potential new treatments for neurological conditions such as Parkinson’s disease, epilepsy, and depression. Moreover, BCIs are set to play an increasingly vital role in neurorehabilitation, aiding individuals in recovering motor functions lost to conditions like paralysis and stroke. As BCI technology advances, it also prompts a deeper examination of the ethical and regulatory aspects of interfacing technology with the human brain, indicating that discussions in these areas will become more prevalent and important. Big space aspirations for 2025 2025 is shaping up to be a landmark year for space exploration , building on the successes of 2024, which included the first successful lunar landing by a private spacecraft. In January, ispace, a Tokyo-based company, will make its second attempt to land on the Moon with the Venture Moon mission, which includes a lander and a micro-rover. Similarly, Houston’s Intuitive Machines will deploy a lander to the Moon’s south pole, carrying crucial instruments like a NASA ice drill and a mass spectrometer to analyze subsurface materials. Additionally, NASA’s Lunar Trailblazer will orbit the Moon to map surface water, further enriching our lunar exploration efforts. The year will also witness significant advancements in studying solar winds with two major missions. The SMILE (Solar Wind Magnetosphere Ionosphere Link Explorer) satellite, a collaboration between the European Space Agency (ESA) and the Chinese Academy of Sciences, aims to explore the interaction of solar wind with Earth’s magnetic field. Simultaneously, NASA’s PUNCH (Polarimeter to Unify the Corona and Heliosphere) mission will use four satellites in low Earth orbit to study the Sun’s atmosphere and produce 3D imagery that will answer long-standing questions about solar energy distribution in the Solar System. NASA’s SPHEREx mission is another highlight of 2025, poised to revolutionize our understanding of the universe. This observatory will map the sky in 102 colors using near-infrared light, collecting data on over 450 million galaxies and more than 100 million Milky Way stars, helping to decode the universe’s origins. Additional notable missions include the Fram2 private space mission by SpaceX, embarking on the first crewed polar orbit spaceflight; the Sierra Space Dream Chaser, testing its reusable spaceplane capabilities with a mission to the ISS; and NASA’s EscaPADE mission, launching on Blue Origin’s New Glenn rocket to study Mars’ magnetosphere, directed by the University of California, Berkeley’s Space Sciences Laboratory. Evolution of humanoid robotics Naturally, since artificial intelligence is getting smarter, in 2025, integrating AI into robotics will further enhance how robots interact with the living world. While the arrival of fully autonomous robots may still be some distance away, there has been considerable progress in developing robots that mimic human capabilities, such as walking, talking, and expressing emotions, thanks to AI. This integration is crucial in taking some of the world’s most advanced robots to the next level. Sophia , for instance, is celebrated for its human-like conversational abilities and facial expressions, utilizing AI to analyze and respond to language effectively. Atlas excels in complex movements and environmental navigation, leveraging AI to handle tasks requiring advanced physical interactions. Unitree, the quadruped robot, is known for its dynamic movement and obstacle navigation, and it is capable of performing intricate maneuvers like backflips. Ameca stands out for its realistic facial expressions, using AI to enhance human-robot interactions. The figure is designed for versatility, employing AI for object recognition and manipulation and adapting effortlessly to various environments. These robots have seen enhancements in their capabilities throughout the year, driven by hardware improvements and AI advancements, further blurring the lines between human and machine interactions. Looking ahead to 2025, the trend of integrating AI to refine decision-making and optimize workflows in robotics is expected to continue. Robot manufacturers are developing generative AI-driven interfaces that allow more intuitive control over robots through natural language, bypassing the need for complex coding. This would enable robots to process and respond to detailed commands, understand complex situations, and even exhibit creative thinking. Developments to watch for include the commercial deployment of robots like the Tesla Bot, an empirical way to gauge the practical use of robotics in everyday environments. Additionally, major investments by leading companies like Amazon or Google, potentially in home robotics, indicate a broader acceptance and integration of robotics in consumer spaces. Further advancements in AI, particularly in computer vision and natural language processing (NLP), will enable robots to perceive their surroundings better and interact more naturally with users. These advancements are moving us to a future where highly autonomous robots are integral to our daily lives. The rebirth of supersonic travel in 2025 Commercial aviation is on the brink of a transformative turn, with advancements in supersonic and hypersonic technologies that will drastically reduce global travel times. These innovations in aircraft design not only focus on speed but are also aimed at achieving quieter, more environmentally friendly supersonic travel, resurrecting a mode of transportation that has waned since Concorde’s retirement. NASA has recently achieved a significant breakthrough with its X-59 quiet supersonic research aircraft. On December 12, at the Skunk Works facility in Palmdale, California, NASA completed the first full burn test, a critical milestone before the project’s full flight testing in 2025. The X-59 is designed to cut down long-distance flight times significantly, both domestically within the United States and internationally. Boom Supersonic is also making advances with its Overture supersonic passenger jet. On December 19, 2024, Boom’s prototype, the XB-1, completed its 10th test flight, achieving a new top speed of Mach 0.95 and reaching an altitude of 32,417 feet, approaching the typical supersonic flight level of about 34,000 feet. This test positions the XB-1 on the cusp of breaking the sound barrier, anticipated in early 2025. Notably, the XB-1’s speed has surpassed the cruising speeds of major commercial aircraft such as the Boeing 787 and Airbus A380, showcasing its potential to revolutionize air travel by combining speed with advanced performance capabilities. Additionally, Venus Aerospace is testing the limits of air travel with its revolutionary hypersonic jet. With the expected inaugural test flight in 2025, this aircraft promises to connect London and New York in just one hour, traveling at speeds up to Mach 6 (3,600 mph/5,795 km/h). The Venus Detonation Ramjet 2000 lb Thrust Engine, or VDR2, is at the core of this development, enabling previously unimaginable speeds that could significantly alter the future of international travel. These advancements signal a historic moment in aviation, where the combined efforts of NASA, Boom Supersonic, and Venus Aerospace initiate a new supersonic era of rapid, efficient, and sustainable air travel. Digging the universe with particle physics In 2025, the particle physics community anticipates the commencement of operations at the European Spallation Source (ESS) in Lund, Sweden. After more than a decade of construction, this state-of-the-art facility will emerge as the world’s most powerful neutron source. Utilizing a high-speed proton beam directed at a heavy-metal target, the ESS will generate intense neutron pulses to probe the structure and dynamics of various materials. This tool will offer scientists unprecedented insights into the properties of matter, supporting advances in energy storage, sustainable technologies, pharmaceuticals, and biological systems. Additionally, research at ESS will explore new materials critical for energy production and storage, such as superconductors and batteries, contributing to solutions for global challenges like climate change, environmental pollution, and resource scarcity. The ESS represents a collaborative effort among 13 European countries, enhancing scientific cooperation and knowledge exchange on a global scale. Simultaneously, plans for the Future Circular Collider (FCC) are progressing at CERN, the European particle-physics laboratory outside Geneva, Switzerland. A detailed feasibility study, expected to conclude in 2025, will assess the financial, technical, and environmental aspects of constructing a massive particle accelerator with a 91-kilometer circumference. This ambitious project, envisioned as the successor to the Large Hadron Collider (LHC), aims to start construction in the 2030s. The FCC will be situated approximately 200 meters underground, a tunnel that could encircle an area larger than Chicago, and is planned to include four experimental halls. The FCC is designed to operate at significantly higher energies than its predecessors, enabling more precise measurements of particles like the Higgs Boson. This enhancement will deepen our understanding of the fundamental laws of nature. It could lead to the discovery of new particles and phenomena that extend beyond the current Standard Model, such as supersymmetry, extra dimensions, and dark matter. These investigations are crucial for unlocking further secrets of the universe.
Dogs as walking buddies
SKOPJE, North Macedonia (AP) — A political party in North Macedonia on Saturday demanded authorities ban social networks whose content incites violence and self-destructive behavior after several young people were seriously injured in connection with the popular “Superman challenge” on TikTok. Health authorities said at least 17 students, ages 10 to 17, were brought to hospitals in the capital Skopje and other towns over the past week with broken bones, contusions and bruises. The children were injured after being thrown into the air by their friends to fly like superheroes and get applause on the internet. The Liberal-Democratic Party, which was part of the left-led coalition that ruled the country from 2016 to earlier in 2024, issued a press statement Saturday strongly condemning “the irresponsible spread of dangerous content on social media, such as the latest TikTok 'challenge' known as ‘Superman,’ which has injured six children across (the country) in the past 24 hours.” “The lack of adequate control over the content of social media allows such ‘games’ to reach the most vulnerable users,” the party statement said. It demanded the “immediate introduction of measures to ban content that incites violence and self-destructive behavior, increase surveillance, and sanction platforms that enable dangerous trends.” North Macedonia’s education minister Vesna Janevska said students should focus on education, not TikTok challenges. “The ban on mobile phones in schools will not have an effect. Phones will be available to children in their homes, neighborhoods and other environments,” she said. Psychologists have warned that the desire to be “in” with the trends on social networks, combined with excessive use of mobile phones, is the main reason for the rise in risky behaviors among children. They urged parents and schools to talk with students.ABILENE, Texas (AP) — Sam Hicks scored on a 53-yard run in the fourth quarter and finished with 171 yards on the ground to lead Abilene Christian to a 24-0 victory over Northern Arizona on Saturday in the first round of the FCS playoffs. The Wildcats (9-4), ranked No. 15 in the FCS coaches poll and seeded 15th, qualified for the playoffs for the first time and will travel to play No. 2 seed and nine-time champion North Dakota State (10-2) on Saturday at the Fargo Dome. The Bison had a first-round bye. Javascript is required for you to be able to read premium content. Please enable it in your browser settings.
The United Nations (UN) General Assembly on Tuesday adopted the UN Convention against Cybercrime, a landmark global treaty that bolsters international cooperation in the fight against such crimes. It is the first international criminal justice treaty negotiated among UN member states in over 20 years. The legally binding convention acknowledges the significant risks posed by the misuse of information and communications technologies, which enable criminal activities on an unprecedented scale, speed, and scope. It highlights the adverse impacts such crimes can have on states, enterprises, and the well-being of individuals and society and focuses on protecting them from offenses such as terrorism, human trafficking, drug smuggling, and online financial crimes. The document also recognizes the growing impact of cybercrime on victims and prioritizes justice, especially for vulnerable groups. It underscores the need for technical assistance, capacity-building and collaboration among states and other stakeholders. According to a UN press release, the convention will open for signature at a formal ceremony to be hosted in Hanoi, Vietnam, next year and enter into force 90 days after being ratified by the 40th signatory. Welcoming the adoption of the historic convention, UN Secretary-General Antonio Guterres expressed his belief that the new treaty will promote a safe cyberspace and called on all states to join it. "This treaty is a demonstration of multilateralism succeeding during difficult times and reflects the collective will of member states to promote international cooperation to prevent and combat cybercrime," his spokesperson said in a statement. "The convention creates an unprecedented platform for collaboration in the exchange of electronic evidence, protection for victims, and prevention while ensuring human rights are protected online," the statement added. Philemon Yang, president of the UN General Assembly, said that with the adoption of the document, countries "have at hand the tools and means to strengthen international cooperation in preventing and combating cybercrime, protecting people and their rights online."Massachusetts Working Class Dramatically Shifted for Trump, Dems Wondering Why
The first half of the SEC Championship proved a rather dour affair, filled with lots of huffing and puffing but little quality in the most important areas of the field. Neither Texas nor Georgia found the end zone in the opening 30 minutes of Saturday's contest, although the Longhorns looked far more efficient with the ball in their possession. Nevertheless, Steve Sarkisian's side limped to just six points despite collecting 200 more yards than the Bulldogs did. One reason why? Penalties. The Longhorns were whistled for eight infractions in the first half, losing a combined 80 yards worth of territory. Georgia, on the other hand, only received two infractions in the same frame. MORE TEXAS-GEORGIA: Live updates from Longhorns-Bulldogs | Who is Matthew Golden? Sarkisian was less than pleased with the disparity in infractions recognized by the officiating crew. In a halftime interview with ESPN's Laura Rutledge, he snapped, firing off a short and snappy response perfectly encapsulating his thoughts on the matter. Here's what you need to know. Steve Sarkisian halftime interview video Steve Sarkisian doesn't seem happy with the officiating 😅 pic.twitter.com/BzUJjxPp7d Sarkisian very well could have set the record for world's quickest interview, serving up 13 words to sum up his dismay with the officiating crew in the first half. "Well, hopefully they call them for a holding one of these times, too," Sarkisian quipped. The Longhorns saw two positive plays knocked off due to offensive holding. Georgia, on the other hand, got off scot-free, only incurring penalties on an unnecessary roughness call and a delay of game. Subjectivity is the name of the game when determining holding calls. It seems luck was not on Texas' side to start the contest. Only time will tell if the refereeing crew evens things up as the game goes on.
The funding that was allocated for outreach efforts during Chicago’s guaranteed income pilot could be a model for how the city reaches communities in other social service programs, according to a newly published report. The University of Chicago’s Inclusive Economy Lab recently published the report as part of their ongoing research into the year-long program, the Chicago Resilient Communities Pilot, which provided 5,000 city residents with $500 for 12 months with no strings attached. The city’s pilot, which ended in 2023, was funded through federal coronavirus pandemic relief funds. The study looked at the administration of the pilot, ranging from the application window to the period once the last checks were distributed to participants. Misuzu Schexnider, program director for financial security at the university’s Inclusive Economy Lab, said that while organizations are usually contracted to run social services, few of them receive funding explicitly to do outreach efforts. “You’re just being paid to serve them,” she said. “You’re not actually being paid to locate them, to recruit, to build trust with them. It’s difficult sometimes to be able to serve that population because you’re not explicitly funded for outreach activities.” During the application window, some people sought in-person assistance programs because they wanted to reach an actual person to ensure the program wasn’t a scam, according to the report. “Especially folks who are less comfortable with virtual or digital forms of communication or relationship, they needed that in-person touch point to be able to feel that this was a real program,” Schexnider said. The YWCA Metropolitan Chicago was the lead contractor for the pilot program, according to the report. In total, there were more than 700 in-person events while the application window was open. About 176,000 people applied for 5,000 slots, which were chosen through a lottery system, according to the report. But the short window of time for the program launch — about three weeks — resulted in organizations contracted by the city facing unexpected overtime because they weren’t able to add staff as quickly, according to the report. The report also outlines how the program ensured the additional cash didn’t result in participants losing other social service benefits. The payments were considered gifts by the Internal Revenue Service because GiveDirectly, a nonprofit, was contracted by the city to administer the payments, according to the report. Chicago’s pilot may have also been the first one to receive an exemption from the the Social Security Administration for Supplemental Security Income and Social Security Disability Insurance, which meant people who receive SSI payments were able to potentially participate in the pilot, said Mary Bogle, a principal research associate at the Urban Institute. “That’s actually huge,” Bogle said. “I haven’t heard of any pilot doing that.” Other pilots across the country discouraged people receiving those types of benefits from applying for guaranteed income pilots because of the risk it posed to keeping their long-term benefits, she said. A second city pilot, rebranded as the Chicago Empowerment Fund , is expected to launch sometime in 2025, according to the city’s proposed budget. The program will again serve 5,000 “low-income families and returning Chicago residents,” and provide $500 for 12 months, but more details about the qualifications weren’t available. The city’s Department of Family and Support Services did not comment on the second pilot’s timeline. While incoming President Donald Trump has vowed to cut government spending, Bogle said many of the pilots weren’t meant to be permanent because they were funded with temporary funds. Future pilots or more permanent guaranteed income programs would likely have to be funded privately or from municipalities’ general funds. Bogle said she thinks that idea could return again once officials realize that today’s employment market isn’t providing the same opportunities as it did during the country’s manufacturing era. “I think this idea is going to keep coming back,” Bogle said. “And I think it’s quite possible that one day in the future – and it could be sooner, it could be later – the conclusion will be that a healthy America needs to offer a consumption floor to its citizens in order for everybody to participate and consume goods.”